Unit 1

1. Pharmacology of drugs acting on cardio vascular system

• Introduction to hemodynamic and electrophysiology
• Drugs used in congestive heart failure
• Anti-hypertensive drugs.
• Anti-anginal drugs.
• Anti-arrhythmic drugs.
• Anti-hyperlipidemic

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Unit 2

1. Pharmacology of drugs acting on cardio vascular system

• Drug used in the therapy of shock.
• Hematinics, coagulants and anticoagulants.
• Fibrinolytics and anti-platelet drugs
• Plasma volume expanders

2. Pharmacology of drugs acting on urinary system

• Diuretics
• Anti-diuretics.

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Unit 3

3. Autocoids and related drugs

• Introduction to autacoids and classification
• Histamine, 5-HT and their antagonists.
• Prostaglandins, Thromboxanes and Leukotrienes.
• Angiotensin, Bradykinin and Substance P. e. Non-steroidal anti-inflammatory agents
• Anti-gout drugs
• Antirheumatic drugs

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Unit 4

5. Pharmacology of drugs acting on endocrine system

• Basic concepts in endocrine pharmacology. b. Anterior Pituitary hormones- analogues and their inhibitors.
• Thyroid hormones- analogues and their inhibitors.
• Hormones regulating plasma calcium level- Parathormone, Calcitonin and Vitamin-D.
• Insulin, Oral Hypoglycemic agents and glucagon.
• ACTH and corticosteroids.

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Unit 5

5. Pharmacology of drugs acting on endocrine system

• Androgens and Anabolic steroids.
• Estrogens, progesterone and oral contraceptives.
• Drugs acting on the uterus.

6. Bioassay

• Principles and applications of bioassay.
• Types of bioassay
• Bioassay of insulin, oxytocin, vasopressin, ACTH,d-tubocurarine, digitalis, histamine and 5-HT

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