Unit 1
👉Impurities in pharmaceutical substances
History of Pharmacopoeia, Sources and types of impurities, principle involved in the limit test for Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals, modified limit test for Chloride and Sulphate
👉General methods of preparation
assay for the compounds superscripted with asterisk (*), properties and medicinal uses of inorganic compounds belonging to the following classes
Unit 2
👉Acids, Bases and Buffers Acids
Buffer equations and buffer capacity in general, buffers in pharmaceutical systems, preparation, stability, buffered isotonic solutions, measurements of tonicity, calculations and methods of adjusting isotonicity.
👉Major extra and intracellular electrolytes: Functions of major physiological ions, Electrolytes used in the replacement therapy
Sodium chloride\*, Potassium chloride, Calcium gluconate* and Oral Rehydration Salt (ORS), Physiological acid base balance.
👉Dental products
Dentifrices, role of fluoride in the treatment of dental caries, Desensitizing agents, Calcium carbonate, Sodium fluoride, and Zinc eugenol cement.
Unit 3
Gastrointestinal agents
👉Acidifiers
Ammonium chloride* and Dil. HCl
👉Antacid
Ideal properties of antacids, combinations of antacids, Sodium Bicarbonate\*, Aluminum hydroxide gel, Magnesium hydroxide mixture
👉Cathartics
Magnesium sulphate, Sodium orthophosphate, Kaolin and Bentonite
👉Antimicrobials
Mechanism, classification, Potassiu permanganate, Boric acid, Hydrogen peroxide\*, Chlorinated lime\*, Iodine and its preparations
Unit 4
Miscellaneous compounds
👉Expectorants
Potassium iodide, Ammonium chloride*.
👉Emetics
Copper sulphate\*, Sodium potassium tartarate
👉Hematinic
Ferrous sulphate\*, Ferrous gluconate
👉Poison and Antidote
Sodium thiosulphate\*, Activated charcoal, Sodium nitrite333
👉Astringents
Zinc Sulphate, Potash Alum
Unit 5
👉Radiopharmaceuticals
Radio activity, Measurement of radioactivity, Properties of α, β, γ radiations, Half life, radio isotopes and study of radio isotopes - Sodium iodide I131, Storage conditions, precautions & pharmaceutical application of radioactive substances.